Publications and Patents

The following represent a selection of recent research publications and patents involving USC Ginsburg IBT researchers:

 

2019 Publications

  • Narala R, Humayun MS, Ameri H. Argus II Retinal Prosthesis Implantation in a Patient With a History Of Strabismus Surgery:A Surgical Technique.  Ophthalmic Surg Lasers Imaging Retina.  50(2):116-119, Feb. 1, 2019.
  • Moysidis SN, Koulisis N, Rodger DC, Chao JR, Leng T, de Carlo T, Burkemper B, Ediriwickrema LS, George MS, Jiang Y, Bohm KJ, Gulati S, Torres RJ, Meallet MA, Moshfeghi AA, Flynn HW Jr, Mieler WF, Williams GA, Humayun MS, Eliott D. Thomas A. Swift’s Electric Rifle Injuries to the Eye and Ocular Adnexa: The Management of Complex Trauma.  Ophthalmol Retina.  3(3):258-269, March 2019.
  • Qian X, Ma T, Shih CC, Heur M, Zhang J, Shung KK, Varma R, Humayun MS, Zhou Q. Ultrasonic Microelastography to Assess Biomechanical Properties of the Cornea.  IEEE Trans Biomed Eng.  66(3):647-655, March 2019.
  • Yu Y, Zhang Z, Cai F, Su M, Jiang Q, Zhou Q, Humayun MS, Qiu W, Zheng H. A Novel Racing Array Transducer for Noninvasive Ultrasonic Retinal Stimulation: A Simulation Study.  Sensors (Basel).  19(8), April 17, 2019.
  • Lin TC, Wang LC, Yue L, Zhang Y, Falabella P, Zhu D, Hinton DR, Rao NA, Birch DG, Spencer R, Dorn JD, Humayun MS. Histopathologic Assessment of Optic Nerves and Retina From a Patient With Chronically Implanted Argus II Retinal Prosthesis System.  Transl Vis Sci Technol. 8(3):31, May 30, 2019.
  • Bodnar ZM, Schuchard R, Myung D, Tarver ME, Blumenkranz MS, Afshari NA, Humayun MS, Morse C, Nischal K, Repka MX, Sprunger D, Trese M, Eydelman MB. Evaluating New Ophthalmic Digital Devices for Safety and Effectiveness in the Context of Rapid Technological Development.  JAMA Ophthalmol.  doi: 10.1001/jamaophthalmol.2019.1576. [Epub ahead of print], June 6, 2019.
  • Rizzo S, Barale PO, Ayello-Scheer S, Devenyi RG, Delyfer MN, Korobelnik JF, Rachitskaya A, Yuan A, Jayasundera KT, Zacks DN, Handa JT, Montezuma SR, Koozekanani D, Stanga P, daCruz L, Walter P, Augustin AJ, Olmos de Koo KC, Ho AC, Kirchhof B, Hahn P, Vajzovic L, Iezzi R, Gaucher D, Arevalo JF, Gregori NZ, Wiedemann P, Ozmert E, Lim JI, Rezende FA, Huang SS, Merlini F, Patel U, Greenberg RJ, Justus S, Bacherini D, Cinelli L, Humayun MS. Hypotony and the Argus II retinal prosthesis: causes, prevention and management.  Br J Ophthalmol.  doi: 10.1136/bjophthalmol-2019-314135. [Epub ahead of print], July 12, 2019.
  • Angelopoulos AN, Ameri H, Mitra D, Humayun M. Enhanced Depth Navigation Through Augmented Reality Depth Mapping in Patients with Low Vision.  Sci Rep.  9(1):11230, Aug. 2, 2019.
  • Jiang L, Yang Y, Chen R, Lu G, Li R, Xing J, Shung KK, Humayun MS, Zhu J, Cheng Y, Zhou Q. Ultrasound‐Induced Wireless Energy Harvesting for Potential Retinal Electrical Stimulation Application. Advanced Functional Materials, p.1902522, 2019.
  • Jiang L, Yang Y, Chen R, Lu G, Li R, Li D, Humayun MS, Shung KK, Zhu J, Chen Y, Zhou Q. Flexible piezoelectric ultrasonic energy harvester array for bio-implantable wireless generator.  Nano Energy.  56:216-224, Feb. 2019.
  • Martinez-Camarillo JC, Spee CK, Chen M, Rodriguez A, Nimmagadda K, Trujillo-Sanchez GP, Hiinton DR, Giarola A, Pikov V, Sridhar A, Humayun MS, Weitz AC. Sympathetic Effects of Internal Carotid Nerve Manipulation on Choroidal Vascularity and Related Measures.  Invest Ophthalmol Vis Sci.  60(13):4303-4309, Oct. 1, 2019.
  • Mulligan K, Seabury S, Dugel PU, Blim JF, Goldman DP, Humayun MS. Economic Value of Anti-Vascular Endothelial Growth Factor Treatment for Patients with Wet Age-Related Macular Degeneration in the United States.  JAMA Ophthalmology.  2019 Nov 14. doi: 10.1001/jamaophthalmol.2019.4557. [Epub ahead of print].

 

2019 Patents

  • Bhadri P, Lescoulie J, Fang S, McCormick M, Kerns R, Humayun M, Barnes Aaron. Enhanced visualization illumination system.  Patent No. 10219695 (Appl. No. 15/680,899).  Filed Aug. 18, 2017.  Issued Mar. 5, 2019.
  • Humayun M, Ahuja A, LePere C. Systems and methods for in vitro and in vivo imaging of cells on a substrate.  Patent No. 10247719 (Appl. No. 15/004,712).  Filed Jan. 22, 2016.  Issued Apr. 2, 2019.
  • Tai YC, Zhao Y, Humayun MS, Weiland JD.  3-coil wireless power transfer system for eye implants.  Patent No. 10251780 (Appl. No. 14/749,487).  Filed Jun. 24, 2015.  Issued Apr. 9, 2019.
  • Humayun M, DeBoer C, Kerns R, McCormick M, Bhadri P, Chong L. Sterile Surgical Tray.  Patent No. 10363165 (Appl. No. 15/656,171).  Filed July 21, 2017.  Issued Jul. 30, 2019.
  • Journey M, Caffey S, Humayun M, Huculak J. Surgical implantation instrument.  Patent No. 10390856 (Appl. No. 13/351,836).  Filed Aug. 27, 2019.

 

2018 Publications

  • Zhang Z, Li F, Chen R, Zhang T, Cao X, Zhang S, Shrout TR, Zheng H, Shung KK, Humayun MS, Qiu W, Zhou Q. High-Performance Ultrasound Needle Transducer Based on Modified PMN-PT Ceramic With Ultrahigh Clamped Dielectric Permittivity.  IEEE Trans Ultrason Ferroelectr Freq Control.  65(2):223-230, Feb. 2018.
  • Lin TC, Yue L, Humayun MS. Retinal Prostheses:  The Argus System.  Technol Innov.  19(3):605-611, 2018.
  • Huang Y, Xu Z, Xiong S, Sun F, Qin G, Hu G, Wang J, Zhao L, Liang YX, Wu T, Lu Z, Humayun MS, So KF, Pan Y, Li N, Yuan TF, Rao Y, Peng B. Repopulated microglia are solely derived from the proliferation of residual microglia after acute depletion.  Nat Neurosci.  21(4):530-540, Apr. 2018.
  • Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had J, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, Humayun MS. A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.  Sci Transl Med.  10(435).  doi: 10.1126/scitranslmed.aao4097, Apr. 4, 2018.
  • Jiang Q, Li G, Zhao H, Sheng W, Yue L, Su M, Weng S, Chan LL, Zhou Q, Humayun MS, Qiu W, Zheng H. Temporal Neuromodulation of Retinal Ganglion Cells by Low-Frequency Focused Ultrasound Stimulation.   IEEE Trans Neural Syst Rehabil Eng.  26(5):969-976, May 2018.
  • Gregori NZ, Callaway NF, Hoeppner C, Yuan A, Rachitskaya A, Feuer W, Ameri H, Arevalo JF, Augustin AJ, Birch DF, Dagnelie G, Grisanti S, Davis JL, Hahn P, Handa JT, Ho AC, Huang SS, Humayun MS, Iezzi R Jr, Jayasundera KT, Kokame GT, Lam BL, Lim JI, Mandava N, Montezuma SR, Olmos de Koo L, Szurman P, Vajzovic L, Wiedemann P, Weiland J, Yan J, Zacks DN. Retinal Anatomy and Electrode Array Position in Retinitis Pigmentosa Patients After Argus II Implantation:  An International Study.  Am J Ophthalmol.  193:87-99, 2018.
  • Qian X, Ma T, Shih CC, Heur M, Jun Z, Shung KK, Varma R, Humayun M, Zhou Q. Ultrasonic Micro-Elastography to Assess Biomechanical Properties of the Cornea.  IEEE Trans Biomed Eng.  doi: 10.1109/TBME.2018.2853571, 2018.
  • Loizos K, Marc R, Humayun M, Anderson JR, Jones BW, Lazzi G. Increasing Electrical Stimulation Efficacy in Degenerated Retina: Stimulus Waveform Design in a Multiscale Computational Model.  IEEE Trans Neural Syst Rehabil Eng.  26(6):1111-1120, Jun. 2018.
  • Qu Y, He Y, Zhang Y, Ma T, Zhu J, Miao Y, Dai C, Humayun M, Zhou Q, Chen Z. Quantified elasticity mapping of retinal layers using synchronized acoustic radiation force optical coherence elastography.  Biomed Opt Express. 9(9):4054-4063, Aug. 2, 2018.
  • Gregori NZ, Callaway NF, Hoeppner C, Yuan A, Rachitskaya A, Feuer W, Ameri H, Arevalo JF, Augustin AJ, Birch DG, Dagnelie G, Grisanti S, Davis JL, Hahn P, Handa JT, Ho AC, Huang SS, Humayun MS, Iezzi R Jr, Jayasundera KT, Kokame GT, Lam BL, Lim JI, Mandava N, Montezuma SR, Olmos de Koo L, Szurman P, Vajzovic L, Wiedemann P, Weiland J, Yan J, Zachs DN. Retinal Anatomy and Electrode Array Position in Retinitis Pigmentosa Patients After Argus II Implantation: An International Study.  Am J Ophthalmol.  193:87-99, September 2018.
  • Trujillo-Sanchez GP, Martinez-Camarillo JC, Spee CK, Hinton DR, Humayun MS, Weitz AC. Stereological Method in Optical Coherence Tomography for In Vivo Evaluation of Laser-Induced Choroidal Neovascularization.  Ophthalmic Surg Lasers Imaging Retina.  49(9):e65-e74, September 1, 2018.
  • Storey PP, Ter-Zakarian A, Philander SA, Olmos de Koo L, George M, Humayun MS, Rodger DC, Ameri H. Visual and Anatomical Outcomes After Diabetic Traction and Traction-Rhegmatogenous Retinal Detachment Repair.  Retina.  38(10):1913-1919, Oct. 2018.
  • Gonzalez-Calle A, Brant R, Diniz B, Swenson S, Markland F, Humayun MS, Weiland JD. Disintegrin-Integrin Binding for Attachment of Polymer Substrate to the Retina.  J Clin Exp Ophthalmol.  9(5) pii: 752. doi: 10.4172/2155-9570.1000752,  8, 2018.
  • Zhang Z, Chen R, Wang B, Zhang T, Su M, Liu R, Yang J, Cao X, Li Y, Zheng H, Shung KK, Humayun MS, Zhou Q, Qui W. Development of a KNN Ceramic-Based Lead-Free Linear Array Ultrasonic Transducer.  IEEE Trans Ultrason Ferroelectr Freq Control.  65(11):2113-2120, Nov. 2018.
  • Thomas BB, Zhu D, Lin TC, Kim YC, Seiler MJ, Martinez-Camarilllo JC, Lin B, Shad Y, Hinton DR, Humayun MS. A new immunodeficient retinal dystrophic rat model for transplantation studies using human-derived cells.  Graefes Arch Clin Exp Ophthalmol.  256(11):2113-2125, Nov. 2018.
  • Rizzo S, Barale PO, Ayello-Scheer S, Devenyi RG, Delyfer MN, Korobelnik JF, Rachitskaya A, Yuan A, Jayasundera KT, Zacks DN, Handa JT, Montezuma SR, Koozekanani D, Stanga PE, da Cruz L, Walter P, Augustin AJ, Chizzolini M, Olmos de Koo LC, Ho AC, Kirchhof B, Hahn P, Vajzovic L, Iezzi R Jr, Gaucher D, Arevalo JF, Gregori NZ, Grisanti S, Ozmert E, Yoon YH, Kokame GT, Lim JI, Szurman P, de Juan E Jr, Rezende FA, Salzmann J, Richard G, Huang SS, Patel U, Cruz C, Greenberg RJ, Justus S, Cinelli L, Humayun MS. Adverse Events of the Argus II Retinal Prosthesis: Incidence, Causes, and Best Practices for Managing and Preventing Conjunctival Erosion.  Retina.  doi: 10.1097/IAE.0000000000002394. [Epub ahead of print], Nov. 20, 2018.

 

2018 Patents

  • Humayun, MS, Murali K, Ribeiro RM, Tai YC, Scianmarello N. Implantable oxygenator with self-contained electrolyte.  Patent No. 9919140 (App. No. 14/433,583).  Filed Oct. 7, 2013.  Issued:  20, 2018.
  • Caffey S, DeBoer C, Humayun M, Tai YC. Filling and implanting accommodative intraocular lenses.  Patent No. 9943405 (App. No. 13/473012).  Filed May 16, 2012.  Issued:  April 17, 2018.
  • Brennan JD, Humayun M. Ophthalmic surgical systems, methods, and devices.  Patent No.  9962226 (App. No. 14/608,915).  Filed Jan. 29, 2015.  Issued:  May 8, 2018.
  • Shih J, Tai YC, Pang C, Caffey S, Peck R, Jiang F, Humayun M. Implantable drug-delivery devices, and apparatus and methods for filling the devices.  Patent No. 9987417 (App. No. 14/706,498.  Filed May 7, 2015.  Issued:  June 5, 2018.
  • Humayun M, Lue JCL. Systems, methods, and devices for cannula insertion.  Patent No. 9999542 (App. No. 14/793,980).  Filed Jul. 8, 2015.  Issued June 19, 2018.
  • Tai YC, Scianmarello NE, DeBoer CMT, Humayun MS. Contact lens with metered liquid system.  Patent No. 10031348 (App. No. 14/881,935).  Filed Oct. 13, 2015.  Issued July 24, 2018.
  • Kerns R, Humayun M, McCormick MT, Wells TS, Chong L, Lue JC. Sterile Surgical Tray.  Patent No. 10070934 (App. No. 15/284,156).  Filed Oct. 3, 2016.  Issued Sept. 11, 2018.
  • Kerns R, Bhadri P, McCormick M, Pinto AGT, Humayun M, Arana L. Adjustable cannula systems and devices.  Patent No.  10076359 (Appl. No. 14/941,412).  Filed Nov. 13, 2015.  Issued September 18, 2018.